EVI2B Antikörper
Kurzübersicht für EVI2B Antikörper (ABIN1302461)
Target
Alle EVI2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD361 Purified
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The mouse monoclonal antibody MEM-216 recognizes an extracellular epitope of CD361 / EVI2B, almost uncharacterized type I transmembrane protein with broad leukocyte expression, mostly in myeloid and B cells.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- Raji cells
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL, Positive control, Positive control: Raji, Daudi, HL-60 cells, peripheral blood lymphcocytes (strongly positive on CD19+ cells), negative control: Jurkat, U-937 cells.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- EVI2B (Ecotropic Viral Integration Site 2B (EVI2B))
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Andere Bezeichnung
- CD361
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Hintergrund
- Ecotropic viral integration site 2B,CD361, also known as EVI2B (ecotropic viral integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.,EVI2B, EVDB
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Gen-ID
- 2124
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UniProt
- P34910
Target
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