hTSH Antikörper

Produktnummer ABIN1301965

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in ELISA, RIA und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für hTSH Antikörper (ABIN1301965)

Target: hTSH

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Radioimmunoassay (RIA), Immunocytochemistry (ICC)

Klon: TSH-51

Produktdetails

Verwendungszweck: Anti-hTSH Purified

Spezifität: The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-51 antibody reacts with association constant 5.5 x 10¹⁰ l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human thyrotropin.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: RIA: The antibody TSH-51 is suitable in combination with the antibody TSH-116 for immunometric assays in the screening of neonatal hypothyroidism.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen

Jirkalová, Cáp, Straková, Príbysová, Plicka, Lomský: "Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism." in: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 10, pp. 823-7, (1997) (PubMed).

Antigendetails

Target: hTSH

Hintergrund: Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.,Thyrotropin