This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 265 kDa in size corresponding to Rif1 by western blotting in the appropriate cell lysate or extract.
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0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." in: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).
Rif1 (also known as telomere-associated protein RIF1 and Rap1-interacting factor 1) is a mouse ortholog of the yeast Rif1 family of telomere-associated proteins identified on the basis of its high expression in primordial germ cells and embryo-derived pluripotent stem cell lines. Mouse Rif1 is a protein involved in negative regulation of telomere length. It is also localized to ATM dependent DNA damage foci and may act at the chromatin level to allow access to some factors. Synonyms: DKFZp781N1478 antibody, FLJ10599 antibody, FLJ11269 antibody, FLJ12870 antibody, Rap1 interacting factor 1 antibody, Rap1 interacting factor 1 homolog antibody, RAP1 interacting factor homolog antibody