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PTENP1 Antikörper (Phosphatase and Tensin Homolog Pseudogene 1) pSer29, pThr32 Primary Antibody

PTENP1 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129639
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target See all PTENP1 products
    PTENP1
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    AA 223-237, pSer29, pThr32
    Reaktivität
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 3
    • 2
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Applikation
    • 5
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Maus, Schaf, Hund, Makake, Schimpanse, Ratte (Rattus)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 223-237 of human PTEN-P1 protein.
    Immunogentype:Recombinant
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 41 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.87 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    PTENP1
    Andere Bezeichnung
    PTEN-P1 (PTENP1 Produkte)
    Synonyme
    PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN, phosphatase and tensin homolog pseudogene 1, PTENP1
    Hintergrund
    This gene (PTENP1) is a highly homologous pseudogene of PTEN.  PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Synonyms: Phosphatase and tensin homolog pseudogene 1 antibody, psiPTEN antibody, PTEN rs antibody, PTEN2 antibody, PTH2 antibody, TEP1 antibody
    Gen-ID
    5728, 73765544
    UniProt
    Q43460
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