Concentration Definition: by UV absorbance at 280 nm
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 155-173 of Mouse DELTA-1. DELTA-1 is a mouse homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Swiss Prot accession Q61483. Expected to cross-react with rat, human and chicken.
Anti-DELTA-1 Antibody has been tested for use in ELISA against the immunizing peptide. It is expected that anti-Delta-1 antibody will be reactive in western blot assays Reactivity in other immunoassays is unknown.
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0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Meliou, Kerezoudis, Tosios, Kiaris: "Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study)." in: The open dentistry journal, Vol. 4, pp. 153-8, (2011) (PubMed).
Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, (2009) (PubMed).
Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene. The Notch signaling pathway has pleiotropic functions during mammalian embryogenesis. It is required for the patterning and differentiation of the presomitic and somitic paraxial mesoderm and of the neural tube. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis, and has been shown to have a role in cell-to-cell communication. Anti-Delta-like protein 1 antibody would be sutiable for researchers in Cell Biology and Signal Transduction. Synonyms: Delta-like protein 1 antibody, Drosophila Delta homolog 1 antibody