APC1 Antikörper (pSer355)

Produktnummer ABIN129636

Produktdetails anti-APC1 Antikörper

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Bindungsspezifität: AA 351-359, pSer355

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität: Maus, Hund, Ratte (Rattus), Schaf

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blot.   Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 215 kDa in size corresponding to APC1 by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Andere Bezeichnung: APC1 (ANAPC1 Produkte)

Synonyme: APC1 antikoerper, MCPR antikoerper, TSG24 antikoerper, DDBDRAFT_0186456 antikoerper, DDBDRAFT_0234263 antikoerper, DDB_0186456 antikoerper, DDB_0234263 antikoerper, 2610021O03Rik antikoerper, AI047775 antikoerper, AI853536 antikoerper, AW547281 antikoerper, Apc1 antikoerper, Mcpr antikoerper, tsg24 antikoerper, EMBRYO DEFECTIVE 2771 antikoerper, MOP10.10 antikoerper, MOP10_10 antikoerper, anaphase promoting complex subunit 1 antikoerper, E3 ubiquitin ligase antikoerper, ANAPC1 antikoerper, Anapc1 antikoerper, CC1G_09696 antikoerper, anapc1 antikoerper, EMB2771 antikoerper

Hintergrund: APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.
Synonyms: Anaphase-promoting complex subunit 1 APC1 Cyclosome subunit 1 Testis-specific gene 24 protein Mitotic checkpoint regulator

Gen-ID: 64682, 12056971

UniProt: Q9H1A4