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EGR1 Antikörper (Early Growth Response 1) AA 94-108 Primary Antibody

EGR1 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (2 references)
Produktnummer ABIN129622
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle EGR1 Antikörper anzeigen
    EGR1
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-108
    Reaktivität
    • 57
    • 33
    • 26
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 48
    • 12
    • 1
    Kaninchen
    Klonalität
    • 47
    • 14
    Polyklonal
    Konjugat
    • 40
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGR1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 23
    • 18
    • 13
    • 13
    • 11
    • 10
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Schimpanse, Maus
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 94-108 (eqpyehltaesfpdi) of Human EGR-1.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band at ~58 kDa in size corresponding to EGR-1 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.93 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Weaver, Hellstrom, Brown, Andrews, Dymov, Diorio, Zhang, Szyf, Meaney: "The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 369, Issue 1652, (2015) (PubMed).

    Hellstrom, Dhir, Diorio, Meaney: "Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 367, Issue 1601, pp. 2495-510, (2012) (PubMed).

  • Target
    EGR1
    Andere Bezeichnung
    EGR-1 (EGR1 Produkte)
    Synonyme
    AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225, A530045N19Rik, ETR103, Egr-1, Krox-1, Krox-24, Krox24, NGF1-A, NGFIA, Zenk, Zfp-6, Zif268, egr, Ngf1, Ngfi, zif-268, EGR1, EGR-1-A, Xegr-1, at225, egr-1, egr1, g0s30, krox-24, ngfi-a, tis8, znf225, krox24, wu:fj64b05, wu:fq25f01, EGR-1, zenk, EGR-1-B, egr1-a, egr1-b, early growth response 1, early growth response protein 1 (egr-1), early growth response 1 L homeolog, early growth response 1 S homeolog, EGR1, CNK00890, Egr1, egr1.L, egr1, egr1.S
    Hintergrund
    EGR-1 (also called Early Growth Response protein 1, Krox-24 protein, ZIF268, Nerve growth factor-induced protein A or NGFI-A, Transcription factor ETR103, and Zinc finger protein 225 or AT225) is a transcriptional regulator that recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site).  EGR-1 activates the transcription of target genes whose products are required for mitogenesis and differentiation.   EGR-1 is a nuclear protein induced by growth factors. Expression has been identified in a variety of cancers.
    Synonyms: AT225 antibody, Early growth response 1 antibody, G0S30 antibody, Krox 24 protein antibody, KROX24 antibody, Nerve growth factor-induced protein A antibody
    Gen-ID
    1958
    UniProt
    P18146
    Pathways
    Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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