BACH1 Antikörper (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1) Isoform 1

Produktnummer ABIN129585

Produktdetails anti-BACH1 Antikörper

Target: BACH1

Bindungsspezifität: AA 92-104, Isoform 1

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BACH1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 92-104 of of human BACH1 protein.
Immunogentype:Recombinant

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 105 -140 kDa in size corresponding to isoforms of BACH1 protein by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu BACH1

Target: BACH1

Andere Bezeichnung: BACH1 (BACH1 Produkte)

Synonyme: zgc:112205, BACH1, 6230421P05Rik, AI323795, BACH-1, BTB domain and CNC homolog 1, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b, BTB and CNC homology 1, basic leucine zipper transcription factor 1, BACH1, bach1b, bach1, Bach1

Hintergrund: BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). The BACH1 gene may be a target of germline cancer-inducing mutations.   BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase.  Two isoforms have been identified for this protein.
Synonyms: BRAC 1 Associated C Terminal Helicase 1 antibody, BRCA 1 Interacting Protein 1 antibody, BRCA1 binding helicase like protein BACH1 antibody, BRCA1 interacting protein C terminal helicase 1 antibody, BRIP 1 antibody

Gen-ID: 83990, 14042978

UniProt: Q9BX63