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ING5 Antikörper (Inhibitor of Growth Family, Member 5) AA 127-140 Primary Antibody

ING5 Reaktivität: Human ELISA, WB Wirt: Ziege Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN129552
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle ING5 Antikörper anzeigen
    ING5
    Bindungsspezifität
    • 10
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-140
    Reaktivität
    • 46
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 4
    Ziege
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ING5 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 28
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 127-140 of Human p28 ING5protein (Inhibitor of growth family, member 5). This sequence shows homology to and 2 for ING5.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 28 kDa or 26 kDa in size corresponding to variants of ING5 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.52 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Iizuka, Sarmento, Sekiya, Scrable, Allis, Smith: "Hbo1 Links p53-dependent stress signaling to DNA replication licensing." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 140-53, (2007) (PubMed).

  • Target
    ING5
    Andere Bezeichnung
    p28 ING5 (ING5 Produkte)
    Synonyme
    p28ING5, 1700001C14Rik, 1700027H23Rik, 1810018M11Rik, AI225768, p28ing5, MGC76007, ING5, MGC133862, ING1, p33, si:busm1-40g1.1, si:dz40g1.1, wu:fc94a02, zgc:100910, ing5, inhibitor of growth family member 5, inhibitor of growth family, member 5, inhibitor of growth family member 5 L homeolog, inhibitor of growth family, member 5b, inhibitor of growth family, member 5a, ING5, Ing5, ing5, ing5.L, ing5b, ing5a
    Hintergrund
    P28 ING5 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.  Multiple alternatively spliced transcript variants have been observed.  The accession number listed below is for variant (1) encodes the longest isoform.
    Synonyms: ING5 antibody, Inhibitor of growth family member 5 antibody
    Gen-ID
    84289, 18644730
    UniProt
    Q8WYH8
    Pathways
    Chromatin Binding
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