Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ING3 Antikörper (Isoform 1)

ING3 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN129551
  • Target Alle ING3 Antikörper anzeigen
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    Bindungsspezifität
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-304, Isoform 1
    Reaktivität
    • 30
    • 19
    • 16
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 26
    • 4
    Ziege
    Klonalität
    • 27
    • 3
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ING3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 12
    • 9
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 294-304 of Human ING3 protein (Inhibitor of growth family, member 3). This sequence only shows homology to for ING3.
    Isotyp
    IgG
    Top Product
    Discover our top product ING3 Primärantikörper
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user.  Expect a band at approximately 47 kDa in size corresponding to ING3 isoform 1 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.10 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    Andere Bezeichnung
    p47 ING3 (ING3 Produkte)
    Synonyme
    ING3 antikoerper, Eaf4 antikoerper, ING2 antikoerper, MEAF4 antikoerper, p47ING3 antikoerper, 1300013A07Rik antikoerper, P47ING3 antikoerper, zgc:56327 antikoerper, inhibitor of growth family member 3 antikoerper, inhibitor of growth family, member 3 antikoerper, inhibitor of growth protein 3 antikoerper, inhibitor of growth family member 3 L homeolog antikoerper, ING3 antikoerper, Ing3 antikoerper, CpipJ_CPIJ009396 antikoerper, ing3 antikoerper, ing3.L antikoerper
    Hintergrund
    P47 ING3 is a tumor suppressor protein similar to ING1 that  can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed.  The accession number listed below is for variant (1) that encodes the longest isoform.
    Synonyms: Inhibitor of growth family member 3 antibody, Inhibitor of growth protein 3 antibody
    Gen-ID
    54556, 38201655
    UniProt
    Q9NXR8
Sie sind hier:
Kundenservice