UBA1 Antikörper

Produktnummer ABIN129529

Produktdetails anti-UBA1 Antikörper

Target: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: Anti-Ubiquitin Activating Enzyme E1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to full length Human Ubiquitin Activating Enzyme E1.
Immunogentype:Recombinant

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.  Expect a band at ~118 kDa in size corresponding to UBE1 by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Restore with deionized water (or equivalent)

Konzentration: 5.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu UBA1

Target: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Andere Bezeichnung: Ubiquitin Activating Enzyme E1 (UBA1 Produkte)

Synonyme: A1S9 antikoerper, A1S9T antikoerper, A1ST antikoerper, AMCX1 antikoerper, GXP1 antikoerper, POC20 antikoerper, SMAX2 antikoerper, UBA1A antikoerper, UBE1 antikoerper, UBE1X antikoerper, DDBDRAFT_0190927 antikoerper, DDBDRAFT_0220497 antikoerper, DDB_0190927 antikoerper, DDB_0220497 antikoerper, Sbx antikoerper, Ube-1 antikoerper, Ube1x antikoerper, a1s9 antikoerper, a1s9t antikoerper, a1st antikoerper, amcx1 antikoerper, gxp1 antikoerper, poc20 antikoerper, smax2 antikoerper, uba1a antikoerper, ube1 antikoerper, ube1x antikoerper, uba1 antikoerper, uba1b antikoerper, ube antikoerper, zgc:66143 antikoerper, wu:fa01e08 antikoerper, wu:fb30f01 antikoerper, wu:fi21c11 antikoerper, wu:fj14g11 antikoerper, ubiquitin like modifier activating enzyme 1 antikoerper, ubiquitin activating enzyme E1 antikoerper, Ubiquitin-conjugating enzyme E1 antikoerper, ubiquitin-like modifier activating enzyme 1 antikoerper, ubiquitin-like modifier activating enzyme 1 S homeolog antikoerper, ubiquitin-like modifier activating enzyme 1 L homeolog antikoerper, UBA1 antikoerper, uae1 antikoerper, GL50803_4083 antikoerper, GL50803_10661 antikoerper, Uba1 antikoerper, uba1.S antikoerper, uba1.L antikoerper, uba1 antikoerper, ptr3 antikoerper

Hintergrund: Ubiquitin Activating Enzyme (E1), also known as A1S9 and UBE1, is responsible for the first step in ubiquitin-protein isopeptide bond formation.  E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. UBE1 is monomeric and contains two active sites within the E1 molecule, allowing it to bind two ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site.  Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR. Isoform 1 has a different 5' noncoding exon compared to isoform 2.  Both variants encode the same protein.
Synonyms: A1S9 antibody, A1S9 protein antibody, A1S9T and BN75 temperature sensitivity complementing antibody, A1S9T antibody, A1ST antibody, GXP 1 antibody

Gen-ID: 7317, 23510338

UniProt: P22314