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UBA1 Antikörper (Ubiquitin-Like Modifier Activating Enzyme 1) Primary Antibody

UBA1 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129529
745,49 €
Zzgl. Versandkosten 20,00 € und MwSt
500 μg
local_shipping Lieferung nach: Deutschland
Lieferung in 5 bis 7 Werktagen
  • Target
    UBA1
    Reaktivität
    • 76
    • 40
    • 32
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 73
    • 3
    Kaninchen
    Klonalität
    • 65
    • 11
    Polyklonal
    Konjugat
    • 26
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBA1 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 39
    • 38
    • 13
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    Anti-Ubiquitin Activating Enzyme E1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to full length Human Ubiquitin Activating Enzyme E1.
    Immunogentype:Recombinant
    Isotyp
    IgG
  • Applikationshinweise
    This purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.  Expect a band at ~118 kDa in size corresponding to UBE1 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Restore with deionized water (or equivalent)
    Konzentration
    5.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    UBA1
    Andere Bezeichnung
    Ubiquitin Activating Enzyme E1 (UBA1 Antibody Abstract)
    Synonyme
    A1S9, A1S9T, A1ST, AMCX1, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, DDBDRAFT_0190927, DDBDRAFT_0220497, DDB_0190927, DDB_0220497, Sbx, Ube-1, Ube1x, a1s9, a1s9t, a1st, amcx1, gxp1, poc20, smax2, uba1a, ube1, ube1x, uba1, uba1b, ube, zgc:66143, wu:fa01e08, wu:fb30f01, wu:fi21c11, wu:fj14g11, ubiquitin like modifier activating enzyme 1, ubiquitin activating enzyme E1, Ubiquitin-conjugating enzyme E1, ubiquitin-like modifier activating enzyme 1, ubiquitin-like modifier activating enzyme 1 S homeolog, ubiquitin-like modifier activating enzyme 1 L homeolog, UBA1, uae1, GL50803_4083, GL50803_10661, Uba1, uba1.S, uba1.L, uba1, ptr3
    Hintergrund
    Ubiquitin Activating Enzyme (E1), also known as A1S9 and UBE1, is responsible for the first step in ubiquitin-protein isopeptide bond formation.  E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. UBE1 is monomeric and contains two active sites within the E1 molecule, allowing it to bind two ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site.  Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR. Isoform 1 has a different 5' noncoding exon compared to isoform 2.  Both variants encode the same protein.
    Synonyms: A1S9 antibody, A1S9 protein antibody, A1S9T and BN75 temperature sensitivity complementing antibody, A1S9T antibody, A1ST antibody, GXP 1 antibody
    Gen-ID
    7317, 23510338
    UniProt
    P22314
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