BIN1 Antikörper

Produktnummer ABIN127306

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BIN1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für BIN1 Antikörper (ABIN127306)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BIN1 Antikörper

Spezifität: The antibody recognizes ~65 kDa band of BIN-1. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples.

Aufreinigung: Immunoaffinity

Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS containing 0.1 % BSA, 30 % glycerol, and 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Andere Bezeichnung: BIN1 / AMPHL

Hintergrund: BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

Gen-ID: 274

NCBI Accession: NP_004296

UniProt: O00499