SDC4 Antikörper

Produktnummer ABIN127275

Dieses Anti-SDC4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SDC4 in WB, IP, IHC (p) und IHC (fro). Geeignet für Human, Maus, Ratte und Huhn.

Kurzübersicht für SDC4 Antikörper (ABIN127275)

Target: SDC4 (Syndecan 4 (SDC4))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SDC4 Antikörper

Spezifität: This antibody detects Syndecan-4.

Aufreinigung: Protein A purified

Immunogen: Synthetic peptide surrounding amino acid 184 of human Syndecan-4

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 5-10 μg/mL. Immunohistochemistry (Frozen and paraffin sections): 15-25 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Andere Bezeichnung: Syndecan-4 (SDC4)

Hintergrund: Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4

Gen-ID: 6385

NCBI Accession: NP_002990

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process