FKBP1A Antikörper

Produktnummer ABIN127265

Der Kaninchen Polyklonal anti-FKBP1A Antikörper wird verwendet zum Nachweis von FKBP1A in Proben von Human, Maus, Ratte, Rind (Kuh) und Kaninchen. Er wurde validiert für WB, IP und IHC (p).

Kurzübersicht für FKBP1A Antikörper (ABIN127265)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FKBP1A Antikörper

Spezifität: The antibody detects 12 kDa FKBP12 protein.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 10 of human FKBP1A/FKBP12.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 2-10 μg/mL. Immunohistochemistry: 2-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP1A / FKBP12

Hintergrund: FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

Gen-ID: 2280

NCBI Accession: NP_000792

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process