FKBP1A Antikörper

Produktnummer ABIN127265

Der Kaninchen-Polyklonal Anti-FKBP1A-Antikörper wurde für WB, IP und IHC (p) validiert. Er ist geeignet zum Nachweis von FKBP1A in Proben aus Human, Maus, Ratte, Rind (Kuh) und Kaninchen. }

Kurzübersicht für FKBP1A Antikörper (ABIN127265)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FKBP1A Antikörper

Spezifität: The antibody detects 12 kDa FKBP12 protein.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 10 of human FKBP1A/FKBP12.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 2-10 μg/mL. Immunohistochemistry: 2-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP1A / FKBP12

Hintergrund: FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

Gen-ID: 2280

NCBI Accession: NP_000792

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process