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LIMK2 Antikörper (C-Term)

Dieses Anti-LIMK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LIMK2 in WB. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN127209

Kurzübersicht für LIMK2 Antikörper (C-Term) (ABIN127209)

Target

Alle LIMK2 Antikörper anzeigen
LIMK2 (LIM Domain Kinase 2 (LIMK2))

Reaktivität

  • 57
  • 33
  • 25
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 48
  • 3
  • 3
  • 2
  • 1
Kaninchen

Klonalität

  • 56
  • 1
Polyklonal

Konjugat

  • 47
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LIMK2 Antikörper ist unkonjugiert

Applikation

  • 49
  • 28
  • 25
  • 14
  • 9
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.

    Aufreinigung

    Affinity Purified

    Immunogen

    Synthetic peptide corresponding to the C-terminus of human LIMK2.
  • Applikationshinweise

    Western Blot: 1-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C/-80 °C

    Informationen zur Lagerung

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Target

    LIMK2 (LIM Domain Kinase 2 (LIMK2))

    Andere Bezeichnung

    LIMK2

    Hintergrund

    LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2

    Gen-ID

    3985

    NCBI Accession

    NP_005560

    UniProt

    P53671
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