MMP13 Antikörper

Produktnummer ABIN127179

Der Kaninchen Polyklonal anti-MMP13 Antikörper (ABIN127179) detektiert spezifisch MMP13 in WB, IP und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Rind (Kuh) und Pferd.

Kurzübersicht für MMP13 Antikörper (ABIN127179)

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MMP13 Antikörper

Spezifität: The antibody recognizes the proenzyme (~60 kDa) and the cleaved fragments (34 kDa and 48 kDa) of MMP-13.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Equine (Horse), Rabbit and Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 454 of Rat MMP-13.

Anwendungsinformationen

Applikationshinweise: Western blotting (0.5-4 μg/mL) . Immunoprecipitation. Immunohistochemistry (works with Paraffin Embedded Sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Andere Bezeichnung: MMP-13

Hintergrund: The Matrix Metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen type I, II, III.Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13

Gen-ID: 4322

NCBI Accession: NP_002418

UniProt: P45452