RAB5 Antikörper

Produktnummer ABIN127153

Produktdetails anti-RAB5 Antikörper

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Spezifität: The antibody recognizes 26 kDa Rab5.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 185 of human Rab5

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation. Immunhistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA as stabilizer and 0.01 % Thimerosal as preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu RAB5

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Andere Bezeichnung: RAB5A / RAB5 (RAB5A Produkte)

Synonyme: RAB5 antikoerper, 2410015H04Rik antikoerper, AI663973 antikoerper, AU021172 antikoerper, nnyRab5a antikoerper, DDBDRAFT_0168594 antikoerper, DDBDRAFT_0229401 antikoerper, DDB_0168594 antikoerper, DDB_0229401 antikoerper, rab5 antikoerper, RAB5A antikoerper, Rab5a antikoerper, rab5al antikoerper, zgc:56644 antikoerper, fj38g08 antikoerper, hm:zehn1144 antikoerper, rab5a antikoerper, wu:fj38g08 antikoerper, RAB5A, member RAS oncogene family antikoerper, rab5A protein antikoerper, Rab5a, GTPase antikoerper, predicted protein antikoerper, Rab GTPase antikoerper, RAB5A, member RAS oncogene family L homeolog antikoerper, RAB5A, member RAS oncogene family, b antikoerper, RAB5A, member RAS oncogene family, a antikoerper, RAB5A antikoerper, Rab5a antikoerper, rab5A antikoerper, rab5a antikoerper, rab5a.L antikoerper, rab5ab antikoerper, rab5aa antikoerper

Hintergrund: Rab5 is a 24 kDa GTP-binding protein that is localized to the cytoplasmic side of the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5 is believed to regulate vesicle fusion through a cycle of GDP/GTP exchange and GTP hydrolysis. The different guanine nucleotide binding states of rab5 is postulated to affect its ability to associate or dissociate with membranes during endocytotic membrane traffic. Its GTP-bound form, which represents the active form of Rab5, associates with membrane and regulates vesicle docking and fusion.Synonyms: Rab-5A, Ras-related protein Rab-5A

Gen-ID: 5868

NCBI Accession: NP_004153

UniProt: P20339

Pathways: Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity