PAWR Antikörper
Kurzübersicht für PAWR Antikörper (ABIN127126)
Target
Alle PAWR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The antibody recognizes PAR4.
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Aufreinigung
- Peptide affinity purified
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Immunogen
- Synthetic peptide surrounding amino acid 327 of human Par4.
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Applikationshinweise
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Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.2 mg/mL
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Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Andere Bezeichnung
- PAR4 / PAWR
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Hintergrund
- Five ionomycin-inducible complementary cDNAs, designated PAR1, 2, 3, 4 and 5, have been isolated from the prostate cancer cell line AT-3. Nucleotide sequencing identified PAR1 as the rat homolog of MKP-1, PAR2 as the injury-inducible gene HB-EGF, and PAR3 as the serum-induced gene cyr-61. PAR4 and PAR5 sequences were not found to correspond to any previously described proteins. PAR4 (prostate apoptosis response-4) is specifically expressed by cells entering apoptosis and is not inducible by growth factor stimulation, oxidative stress and necrosis, or growth arrest. The PAR4 gene encodes a 38 kDa protein with a putative nuclear localization signal and carboxy terminal leucine zipper.Synonyms: PRKC apoptosis WT1 regulator protein, Par-4, Prostate apoptosis response 4 protein
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Gen-ID
- 5074
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NCBI Accession
- NP_002574
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UniProt
- Q96IZ0
Target
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