CETP Antikörper (C-Term)

Produktnummer ABIN127095

Produktdetails anti-CETP Antikörper

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CETP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody recognizes 70 kDa CETP.

Aufreinigung: Peptide affinity purified

Immunogen: Synthetic peptide corresponding to the C-terminus of human CETP.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Andere Bezeichnung: CETP (CETP Produkte)

Hintergrund: It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.Synonyms: Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I

Gen-ID: 1071

NCBI Accession: NP_000069

UniProt: P11597