RGS3 Antikörper (AA 401-519)

Produktnummer ABIN127074

Dieses Anti-RGS3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RGS3 in WB und IP. Geeignet für Human.

Kurzübersicht für RGS3 Antikörper (AA 401-519) (ABIN127074)

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-RGS3 Antikörper

Bindungsspezifität: AA 401-519

Spezifität: This antibody detects human RGS3. Other species not tested.

Aufreinigung: Protein A chromatography

Immunogen: E. coli-expressed human RGS3 (aa 401-519)

Anwendungsinformationen

Applikationshinweise: Western Blot: 1.0 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Details zu RGS3

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Andere Bezeichnung: RGS3

Hintergrund: RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Giα and Gαq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.Synonyms: RGP3, Regulator of G-protein signaling 3

Gen-ID: 5998

NCBI Accession: NP_060260

UniProt: P49796

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling