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Hepatitis E Virus Antikörper

HEV Reaktivität: Human EIA Wirt: Maus Monoclonal S-13 unconjugated
Produktnummer ABIN126703
  • Target Alle Hepatitis E Virus (HEV) Produkte
    Hepatitis E Virus (HEV)
    Reaktivität
    • 5
    • 2
    Human
    Wirt
    • 6
    • 1
    Maus
    Klonalität
    • 6
    • 1
    Monoklonal
    Konjugat
    • 7
    Dieser Hepatitis E Virus Antikörper ist unkonjugiert
    Applikation
    • 7
    • 4
    • 3
    Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography on Protein G.
    Immunogen
    A highly antigenic polypeptide consisting of essential sequences at least 30 residues in length which were selected from gene encoding ORF3 region of a Chinese HEV strain.
    Klon
    S-13
    Isotyp
    IgM
  • Applikationshinweise
    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Double distillated water is recommended to adjust the final concentration to 1.0 mg/mL.
    Konzentration
    1.0 mg/mL
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt store at -20 °C.
  • Target
    Hepatitis E Virus (HEV)
    Andere Bezeichnung
    Hepatitis E Virus / HEV (HEV Produkte)
    Substanzklasse
    Virus
    Hintergrund
    Hepatitis E is a viral hepatitis (liver inflammation) caused by infection with a virus called hepatitis E virus (HEV). HEV is a positive-sense single-stranded RNA icosahedral virus with a 7.5 kilobase genome. HEV has a fecal-oral transmission route. It is one of five known hepatitis viruses: A, B, C, D, and E. The HEV genome is approximately 7200 bases in length, is a polyadenylated single-strand RNA molecule that contains three discontinuous and partially overlapping open reading frames (ORFs) along with 5' and 3' cis-acting elements, which have important roles in HEV replication and transcription. ORF1 encode a methyltransferase, protease, helicase and replicase, ORF2 encode the capsid protein and ORF3 encodes a protein of undefined function. The hepatitis E virus causes around 20 million infections a year. These result in around three million acute illnesses and 70,000 deaths annually. It is particularly dangerous for pregnant women, who can develop an acute form of the disease that is lethal in 20 per cent of cases. The virus (HEV) is a major cause of illness and of death in the developing world and disproportionate cause of deaths among pregnant women.
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