CXCR6 Antikörper (AA 11-25)

Produktnummer ABIN126328

Produktdetails anti-CXCR6 Antikörper

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Bindungsspezifität: AA 11-25

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: SP1286P recognises the orphan G protein-coupled chemokine receptor CXCR6, also known as CDw186. CXCR6 has been identified as a co-receptor for simian immunodeficiency virus (SIV), HIV-2 and HIV-1. Lymphoid tissues and activated peripheral blood lymphocytes express CXCR6 mRNA.

Aufreinigung: Affinity purified immunoglobulin fraction

Immunogen: Peptide corresponding to aa 11 to 25 of human CXCR6/CDw186 (NT)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot (1/500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C or at -20 °C if preferred. Avoid repeated freezing and thawing.
Shelf Life: One year from despatch.

Haltbarkeit: 12 months

Details zu CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Andere Bezeichnung: CD186 / CXCR6 (CXCR6 Produkte)

Synonyme: BONZO antikoerper, CD186 antikoerper, STRL33 antikoerper, TYMSTR antikoerper, BB217514 antikoerper, C-X-C motif chemokine receptor 6 antikoerper, chemokine (C-X-C motif) receptor 6 L homeolog antikoerper, chemokine (C-X-C motif) receptor 6 antikoerper, CXCR6 antikoerper, cxcr6.L antikoerper, Cxcr6 antikoerper

Hintergrund: Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR

Gen-ID: 10663

UniProt: O00574