Cytokeratin 1 Antikörper (pan)

Produktnummer ABIN126063

Dieses Anti-Cytokeratin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cytokeratin 1 in IHC (p) und IHC (fro). Geeignet für Human und Säugetier.

Kurzübersicht für Cytokeratin 1 Antikörper (pan) (ABIN126063)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reaktivität: Human, Säugetier

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Cytokeratin 1 Antikörper

Bindungsspezifität: pan

Spezifität: This antibody reacts positively with all stratified squamous epithelia and epidermal appendages such as hairfollicles, sebaceous glands. Also positive on epithelia of the urinary tract, stomach, intestine, uterine endometrium and prostate. Identifies mesotheliomas, squamous cell carcinomas, adenocarcinomas, transitional cell carcinomas and anaplastic carcinomas.

Kreuzreaktivität (Details): Species reactivity (tested):Human and most Mammals (including Mouse).

Aufreinigung: Affinity Chromatography.

Immunogen: Human skin.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Frozen and Paraffin-Embedded Tissue (With Paraffin Sectionsproteolytic treatment with Trypsin is recommended). Working Dilution: 1/50 (optimize by serial dilution). Dilution Buffer: Dilute immediately before use with PBS or TBS. Incubation time: 1 h at room temperature. Recommended Positive Control: Squamous cell carcinoma, skin, cervix.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS or TBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Andere Bezeichnung: Cytokeratin

Hintergrund: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Synonyms: Cytokeratin pan-reactive, pan Keratin