CD9 Antikörper

Produktnummer ABIN125680

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD9 in FACS, WB, IHC (p), Func und MS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CD9 Antikörper (ABIN125680)

Target: CD9

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD9 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Mass Spectrometry (MS)

Klon: MEM-61

Produktdetails anti-CD9 Antikörper

Verwendungszweck: Anti-Hu CD9 Purified Azide Free

Spezifität: The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Pre-B cell line NALM-6.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Functional application: The antibody MEM-61 induces FcγR-dependent platelet aggregation.
Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: Recommended dilution: 2-4 μg/mL, non-reducing conditions.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: prostate.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Konservierungsmittel: Azide free

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-CD9 Antikörper (ABIN125680)

Singh, Sugimoto, Dhawan, Harris: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." in: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).

Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).

Details zu CD9

Target: CD9

Andere Bezeichnung: CD9

Hintergrund: CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2

Gen-ID: 928

UniProt: P21926

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization