Cytokeratin 19 Antikörper (Biotin)
Kurzübersicht für Cytokeratin 19 Antikörper (Biotin) (ABIN125675)
Target
Alle Cytokeratin 19 (KRT19) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Cytokeratin 19 Biotin
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The antibody BA-17 reacts with cytokeratin 19 (40 kDa intracellular antigen) in human tissue. Cytokeratin 19 is not expressed in hepatocytes, it is often co-expressed with cytokeratin 7.
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Aufreinigung
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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Immunogen
- Mammary organoids.
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Isotyp
- IgG1, kappa
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Applikationshinweise
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Western blotting: Recommended dilution: 1-2 μg/mL.
Flow cytometry: Recommended dilution: 4-10 μg/mL. Intracellular staining. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer." in: Genes & development, Vol. 17, Issue 24, pp. 3127-38, (2003) (PubMed).
: "A subclass of luminal epithelial cells in the human mammary gland, defined by antibodies to cytokeratins." in: Journal of cell science, Vol. 75, pp. 17-33, (1985) (PubMed).
: "Patterns of expression of keratin 19 as detected with monoclonal antibodies in human breast tissues and tumours." in: International journal of cancer. Journal international du cancer, Vol. 36, Issue 3, pp. 299-306, (1985) (PubMed).
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Andere Bezeichnung
- Cytokeratin 19
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Hintergrund
- Keratin 19,Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.,K19, CK19, CYK19, KRT19, K1CS
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Gen-ID
- 3880
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UniProt
- P08727
Target
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