GRPR Antikörper (Cytoplasmic Domain)

Produktnummer ABIN122617

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRPR in IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GRPR Antikörper (Cytoplasmic Domain) (ABIN122617)

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRPR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-GRPR Antikörper

Bindungsspezifität: Cytoplasmic Domain

Spezifität: Reacts with Gastrin-releasing peptide receptor at 3rd cytoplasmic domain. BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except ADAM28 (41 %).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat (see 'Immunogen Remarks').
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunocytochemistry: 5 μg/mL. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin embedded sections. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GRPR

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Andere Bezeichnung: Gastrin-Releasing Peptide Receptor

Hintergrund: Gastrin-releasing peptide receptor (GRPR) is a bombesin receptor. In addition to its involvement in autism and mental retardation, GRPR may also play a role in the progression of cancer. Nicotine exposure induces an increase in GRPR expression in the lung. GRPR has been reported in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach, and uterus. It has also been shown to be expressed in several cancers, including those in breast, colon, lung, ovary, pancreas, and prostate.Synonyms: GRP-R, GRP-preferring bombesin receptor, GRPR

Gen-ID: 2925

UniProt: P30550