PAK6 Antikörper (Linker Domain)

Produktnummer ABIN122606

Produktdetails anti-PAK6 Antikörper

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Bindungsspezifität: Linker Domain

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with P21-Activated Kinase 6 (PAK6) (family: Protein Kinase, subfamily: PAK (STE20))

Produktmerkmale: Synonyms: p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugatedEpitope: Linker domain of humanGenename: PAK6

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 3,5 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6 (PAK6 Produkte)

Synonyme: PAK5 antikoerper, 4732456M09 antikoerper, pak6 antikoerper, si:ch211-158b22.3 antikoerper, p21 (RAC1) activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6b antikoerper, PAK6 antikoerper, Pak6 antikoerper, pak6b antikoerper

Hintergrund: PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac, however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 also has been called P21-Activated Kinase 5 (PAK5), however, PAK5 is a distinct gene found on chromosome 20 p12.2. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6

Gen-ID: 56924

UniProt: Q9NQU5