TACR1 Antikörper (C-Term)

Produktnummer ABIN122523

Dieses Anti-TACR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TACR1 in IHC (p). Geeignet für Human, Ratte, Maus, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen und Hamster.

Kurzübersicht für TACR1 Antikörper (C-Term) (ABIN122523)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TACR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TACR1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Tachykinin receptor 1 (TACR1) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DTNB (44 %).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Immunoaffinity chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 1-40 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Hintergrund: Tachykinin receptor 1, a member of the tachykinin receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R

Gen-ID: 6869

UniProt: P25103

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration