GHRHR Antikörper (C-Term)

Produktnummer ABIN122454

Dieses Anti-GHRHR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GHRHR in IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für GHRHR Antikörper (C-Term) (ABIN122454)

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GHRHR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GHRHR Antikörper

Bindungsspezifität: C-Term

Spezifität: Reacts with Growth Hormone Releasing Hormone Receptor (family: GPCR, subfamily: Growth hormone releasing hormone)

Aufreinigung: Peptide Immunogen Affinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GHRHR

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Andere Bezeichnung: GHRH Receptor

Hintergrund: GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific. GHRHR has been reported to be expressed primarily in the brain. ESTs have been isolated from brain and pituitary libraries.Synonyms: GHRHR, GRF receptor, GRFR, Growth hormone-releasing factor receptor, Growth hormone-releasing hormone receptor

Gen-ID: 2692

UniProt: Q02643

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process