GRM2 Antikörper (N-Term)

Produktnummer ABIN122313

Dieses Anti-GRM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRM2 in WB, IF und IHC (p). Geeignet für Human, Ratte, Maus, Rind (Kuh) und Schwein.

Kurzübersicht für GRM2 Antikörper (N-Term) (ABIN122313)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GRM2 Antikörper

Bindungsspezifität: N-Term

Spezifität: Reacts with Metabotropic Glutamate Receptor 2 (family: GPCR, subfamily: Metabotropic glutamate)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine, PigSpecies reactivity (tested):Human

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 5-10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 to -80 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Andere Bezeichnung: mGluR2 / GRM2

Hintergrund: The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).Synonyms: GPRC1B, Metabotropic glutamate receptor 2

Gen-ID: 2912

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport