HNF4 gamma Antikörper

Produktnummer ABIN122270

Der Kaninchen Polyklonal anti-HNF4 gamma Antikörper wird verwendet zum Nachweis von HNF4 gamma in Proben von Human und Maus. Er wurde validiert für IHC (p).

Kurzübersicht für HNF4 gamma Antikörper (ABIN122270)

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF4 gamma Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HNF4 gamma Antikörper

Spezifität: Reacts with Hepatocyte Nuclear Factor 4 Gamma (HNF4 Gamma/NR2A2) (family: NHR, subfamily: NR2 Hepatocyte NF4-like)

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 16-32 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu HNF4 gamma

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Andere Bezeichnung: HNF4 gamma / NR2A2

Hintergrund: Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 - 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver. Ligand: Saturated and cis-monounsaturated C14-18 fatty acidsSynonyms: Hepatocyte nuclear factor 4-gamma, Nuclear receptor subfamily 2 group A member 2

Gen-ID: 3174

UniProt: Q14541

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway