LPAR5 Antikörper

Produktnummer ABIN122193

Der Kaninchen Polyklonal anti-LPAR5 Antikörper (ABIN122193) detektiert spezifisch LPAR5 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für LPAR5 Antikörper (ABIN122193)

Target: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LPAR5 Antikörper

Spezifität: Reacts to G Protein-Coupled Receptor GPR92/GPR93 (Family: GPCR, Subfamily: Orphan-A)

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 1.5 -4 μg/mL (for details please see Protocols below).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu LPAR5

Target: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Andere Bezeichnung: LPAR5 / GPR92 / GPR93

Hintergrund: GPR92/GPR93 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity and led to an increase in both phosphoinositide hydrolysis and c-AMP production. GPR92 is atypical in that it has a low sequence homology with the classic LPA receptors (21-22 % ). The expression of GPR92 is mainly found in brain, testis, heart, placenta, spleen, lung, and gut. Notably, GPR92 is highly expressed in the lymphocyte compartment of the gastrointestinal tract. It is the most abundant GPCR that is activated by LPA found in the small intestinal intraepithelial CD8+ cytotoxic T cells.Synonyms: 93, G-protein coupled receptor 92, LPA receptor 5, LPA-5, Lysophosphatidic acid receptor 5

Gen-ID: 57121

UniProt: Q9H1C0