CXCR5 Antikörper (Cytoplasmic Domain)

Produktnummer ABIN121946

Der Kaninchen Polyklonal Anti-CXCR5-Antikörper wurde für IHC (p) validiert. Er ist geeignet, CXCR5 in Proben von Human zu detektieren.

Kurzübersicht für CXCR5 Antikörper (Cytoplasmic Domain) (ABIN121946)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CXCR5 Antikörper

Bindungsspezifität: Cytoplasmic Domain

Spezifität: Recognizes Human CXC Chemokine Receptor 5 (CXCR5) (family: GPCR, subfamily: Chemokine). BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except MTA3 (50 %).

Kreuzreaktivität (Details): Species reactivity (expected):Hamster, Mouse, Pig, Rabbit, Rat.
Species reactivity (tested):Human, Gibbon, Gorilla.

Aufreinigung: Peptide Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 5-18 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for up to one month or at -70 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Andere Bezeichnung: CD185 / CXCR5

Hintergrund: CXCR5, a Chemokine Receptor, is required for normal development of Peyer's patches, inguinal lymph nodes, and splenic follicles. CXCR5 binds B-lymphocyte chemoattractant (BLC) and is involved in B-cell homing to follicles in lymph nodes and spleen. Two isoforms are produced by alternative splicing. CXCR5 expression has been reported in human blood and salivary gland and in animal lymphatic organs, blood, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil. ESTs have been isolated from human brain, germ cell, lung, lymph, pancreas, skin, stomach, and uterus cancer libraries, and from normal human blood, liver/spleen, lymph node, nerve, placenta, small intestine, tonsil, and B-cell/lung/testis libraries.Synonyms: BLR1, Burkitt lymphoma receptor 1, C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, MDR15, Monocyte-derived receptor 15

Gen-ID: 643

UniProt: P32302