CrkL Antikörper (C-Term)

Produktnummer ABIN121674

Der Ziege Polyklonal anti-CrkL Antikörper (ABIN121674) detektiert spezifisch CrkL in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CrkL Antikörper (C-Term) (ABIN121674)

Target: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CrkL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CrkL Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide sequence KIFDPQNPDENE derived from C-terminus of CRKL

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/200 - 1/500, this antibody detects a band of approximately 33 kDa in mouse kidney cell lysates, overnight incubation with primary antibody is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: TRIS buffered saline pH 7.3 containing 0.02 % Sodium Azide and 0.5 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu CrkL

Target: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Andere Bezeichnung: CRKL

Hintergrund: CRKL is a 33 kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS-dependant manner. CRKL is a substitute of BCR-ABL tyrosine kinase.Synonyms: Crk-like protein, v-crk avian sarcoma virus CT10 oncogene homolog-like

Pathways: Interferon-gamma Pathway, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor