DC-SIGN/CD209 Antikörper (AA 277-293)

Produktnummer ABIN121620

Dieses Anti-DC-SIGN/CD209-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DC-SIGN/CD209 in WB, IF und IHC (fro). Geeignet für Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (AA 277-293) (ABIN121620)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DC-SIGN/CD209 Antikörper

Bindungsspezifität: AA 277-293

Spezifität: This antibody recognizes an epitope within the extracellular domain of CD209/DC-SIGN.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic peptide corresponding to amino acids 277-293 of human DC-SIGN

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 μg/mL - 2 μg/mL, This antibody detects a band of approximately 44 kD by western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209 / DC-SIGN

Hintergrund: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV1, HIV2 and SIV bind to DCs via DCSIGN. ICAM3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed CD299, DC-SIGNR, L-SIGN and DCSIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

UniProt: Q9NNX6