HTRA2 Antikörper (AA 134-458)

Produktnummer ABIN121159

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HTRA2 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für HTRA2 Antikörper (AA 134-458) (ABIN121159)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HTRA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 1B3

Produktdetails anti-HTRA2 Antikörper

Bindungsspezifität: AA 134-458

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human HtrA2/Omi (134-458 aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1:500 - 1:2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HTRA2 / PRSS25

Hintergrund: HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Recently, HtrA2 has been known to contribute both to caspase-dependent and caspase-independent cell death.Synonyms: High temperature requirement protein A2, OMI, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, mitochondrial Serine protease HTRA2

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity