CD8 Antikörper (PE)
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- Target Alle CD8 Antikörper anzeigen
- CD8
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody recognizes a conformationally-dependent epitope of CD8 antigen.
- Produktmerkmale
- Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain
- Immunogen
- Crude thymus membrane fraction.
- Klon
- MEM-31
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD8 Primärantikörper
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- Applikationshinweise
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Flow Cytometry analysis of human blood cells using 20 l reagent / 100 l whole blood or10^6 cells in a suspension. Does not work in Immunohistocchemistry omn paraffin sections or Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Lagerung
- 4 °C
- Informationen zur Lagerung
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Store at 2-8 °C. Do not freeze. Avoid prolonged exposure to light.
Shelf life: one year fromdespatch. - Haltbarkeit
- 12 months
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- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Hintergrund
- The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as ab heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as aa homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8b level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 a-b but not a-a dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
- Gen-ID
- 925
- UniProt
- P01732
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