CD52 Antikörper

Produktnummer ABIN120666

Produktdetails anti-CD52 Antikörper

Target: CD52

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD52 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody Clone HI186 reacts with CD52, a 25-29 kDa glycoprotein containing a large N-linked carbohydrate moiety. Mature CD52 Molecule is actually much smaller (approx. 8-9 kDa).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: Human tonsil

Klon: HI186

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry: use 5 μL of neat antibody to label 10^6 cells. Immunohistochemistry on frozen and paraffin embedded sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD52

Target: CD52

Andere Bezeichnung: CD52 / CAMPATH-1 (CD52 Produkte)

Synonyme: CD52 antikoerper, AI463198 antikoerper, B7 antikoerper, B7-Ag antikoerper, CAMPATH-1 antikoerper, CLS1 antikoerper, MB7 antikoerper, CDW52 antikoerper, CE5 antikoerper, CD52 molecule antikoerper, CD52 antigen antikoerper, CD52 antikoerper, Cd52 antikoerper

Hintergrund: CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

Gen-ID: 1043

UniProt: P31358