KRT8 Antikörper

Produktnummer ABIN120663

Zitiert in 1 Publikation. Der Maus Monoklonal anti-KRT8 Antikörper (Klon C-43) (ABIN120663) detektiert spezifisch KRT8 in WB, IF, IHC (p) und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Kaninchen, Schwein und Schaf.

Kurzübersicht für KRT8 Antikörper (ABIN120663)

Target: KRT8 (Keratin 8 (KRT8))

Reaktivität: Human, Rind (Kuh), Kaninchen, Schwein, Schaf

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Klon: C-43

Produktdetails anti-KRT8 Antikörper

Spezifität: The antibody C-43 reacts with Cytokeratin 8 (52.5 kDa).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Cytoskeleton preparation from HeLa human cervix carcinoma cell line

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Western Blot. Immunocytochemistry. Immunohistochemistry (Paraffin): 20 m g/mL. Positive tissue: prostate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-KRT8 Antikörper (ABIN120663)

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, (1991) (PubMed).

Details zu KRT8

Target: KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung: Cytokeratin 8

Hintergrund: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8

Molekulargewicht: 52.5 kDa

Gen-ID: 3856

UniProt: P05787