CD8 Antikörper
-
- Target Alle CD8 Antikörper anzeigen
- CD8
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD8 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- The antibody recognizes CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.
- Produktmerkmale
- Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain
- Aufreinigung
- Protein-A affinity chromatography
- Reinheit
- > 95 % pure (by SDS-PAGE)
- Immunogen
- Leucocytes of a patient suffering from LGL Type Leukaemia
- Klon
- MEM-87
- Isotyp
- IgG1
- Top Product
- Discover our top product CD8 Primärantikörper
-
anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reaktivität: Human, Maus, Ratte FACS, IHC (fro), WB, ELISA, IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human FACS, IP, CyTOF Wirt: Maus Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (Biotin)CD8 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibody (FITC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human IHC, IP, WB, ELISA Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD8 (CD8) antibody (PerCP)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PerCP
anti-CD8 (CD8) antibody (APC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 APC
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Cat FACS Wirt: Maus Monoclonal fCD8 PE
-
- Applikationshinweise
-
Immunoprecipitation (Excellent for immunoisolation of CD8 + T cells). Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
-
- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Hintergrund
- The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as ab heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as aa homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8b level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 a-b but not a-a dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling. CD8 is a disulfide-linked dimer and exists as a CD8a homodimer or CD8a/b heterodimer (each monomer approx. 32-34 kDa).Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
- Gen-ID
- 925
- UniProt
- P01732
-
