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CD7 Antikörper (FITC)

CD7 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-186 FITC

Produktnummer ABIN120615

Datenblatt (PDF)

Target Alle CD7 Antikörper anzeigen

CD7
Reaktivität
183

25

10

10

6
Human
Wirt
106

78

1

1
Maus
Passende Sekundärantikörper
Klonalität
111

74

1
Monoklonal
Konjugat
76

17

13

12

8

6

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD7 Antikörper ist konjugiert mit FITC
Applikation
113

58

45

31

29

17

15

12

8

6

3

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Immunogen

Human acute myelogenous leukaemia cell line KG-1

Klon

MEM-186

Isotyp

IgG1

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anti-CD7 (CD7) (AA 26-180) antibody
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anti-CD7 (CD7) antibody
CD7 Reaktivität: Human FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-186 unconjugated

anti-CD7 (CD7) (AA 72-175) antibody
CD7 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 5B10E3 unconjugated

anti-CD7 (CD7) (AA 26-180) antibody
CD7 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2B1C9 unconjugated

anti-CD7 (CD7) antibody
CD7 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated

anti-CD7 (CD7) (AA 24-150) antibody
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anti-CD7 (CD7) (AA 21-240) antibody
CD7 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1B8 unconjugated

anti-CD7 (CD7) antibody
CD7 Reaktivität: Human IHC Wirt: Kaninchen Monoclonal MSVA-007R unconjugated Recombinant Antibody

Applikationshinweise

Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Haltbarkeit

12 months
Target

CD7

Andere Bezeichnung

CD7 (CD7 Produkte)

Hintergrund

CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gen-ID

924

UniProt

P09564

Pathways

Cell-Cell Junction Organization