2B4 Antikörper

Produktnummer ABIN120312

Der Maus Monoklonal anti-2B4 Antikörper (Klon 2B4-69) (ABIN120312) detektiert spezifisch 2B4 in FACS und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für 2B4 Antikörper (ABIN120312)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser 2B4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: 2B4-69

Produktdetails anti-2B4 Antikörper

Spezifität: This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 106 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Andere Bezeichnung: CD244

Hintergrund: The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4

Gen-ID: 51744

NCBI Accession: NP_001160135

UniProt: Q9BZW8