Integrin beta 3 Antikörper (PE)

Produktnummer ABIN120252

Dieses Anti-Integrin beta 3-Antikörper ist ein Hamster Monoklonal-Antikörper zur Detektion von Integrin beta 3 in FACS. Geeignet für Maus und Ratte.

Kurzübersicht für Integrin beta 3 Antikörper (PE) (ABIN120252)

Target: Integrin beta 3 (ITGB3)

Reaktivität: Maus, Ratte

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: HM beta 3-1

Produktdetails anti-Integrin beta 3 Antikörper (PE)

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Neat-1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.0 mL distilled water

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Andere Bezeichnung: CD61 / ITGB3

Hintergrund: CD61 is a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa

Gen-ID: 10090

UniProt: O54890

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex