CD177 Antikörper

Produktnummer ABIN119768

Der Maus Monoklonal anti-CD177 Antikörper wird verwendet zum Nachweis von CD177 in Proben von Human und Primate. Er wurde validiert für WB, IP und FACS.

Kurzübersicht für CD177 Antikörper (ABIN119768)

Target: CD177 (CD177 Molecule (CD177))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD177 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: MEM-166

Produktdetails anti-CD177 Antikörper

Spezifität: This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Non-Human Primates.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Human Granulocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated thawing and freezing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.

Details zu CD177

Target: CD177 (CD177 Molecule (CD177))

Andere Bezeichnung: CD177

Hintergrund: CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1

Gen-ID: 57126

NCBI Accession: NP_065139

UniProt: Q8N6Q3