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Calcitonin Receptor Antikörper (Cytoplasmic Domain)

Der Maus Monoklonal Anti-Calcitonin Receptor-Antikörper wurde für WB, IF, FACS, IHC (p), IHC (fro) und EIA validiert. Er ist geeignet, Calcitonin Receptor in Proben von Human und Kaninchen zu detektieren.
Produktnummer ABIN119693

Kurzübersicht für Calcitonin Receptor Antikörper (Cytoplasmic Domain) (ABIN119693)

Target

Alle Calcitonin Receptor (CALCR) Antikörper anzeigen
Calcitonin Receptor (CALCR)

Reaktivität

  • 55
  • 22
  • 21
  • 2
  • 1
  • 1
Human, Kaninchen

Wirt

  • 69
  • 8
Maus

Klonalität

  • 71
  • 6
Monoklonal

Konjugat

  • 35
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Calcitonin Receptor Antikörper ist unkonjugiert

Applikation

  • 48
  • 26
  • 26
  • 26
  • 18
  • 16
  • 14
  • 14
  • 13
  • 8
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon

31-01-14
  • Bindungsspezifität

    • 15
    • 15
    • 11
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain

    Spezifität

    This antibody recognizes the Calcitonin Receptor. Clone 31/01 recognizes an epitope within the cytoplasmic domain that is common to both C1a and C1b Human isoforms.

    Aufreinigung

    Affinity Chromatography on Protein A.

    Immunogen

    Synthetic peptide derived from a sequence within the cytoplasmic domain of Human Calcitonin Receptor. Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line.

    Isotyp

    IgG2a
  • Applikationshinweise

    ELISA: 1/1000 - 1/5000. Immunohistochemistry on paraffin sections: 1/50 - 1/500, we recommend the use of 4 % paraformaldehyde fixation, rather than formalin fixation, This product does not require protein digestion pre-treatment of paraffin embedded sections, This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections. Recommended Positive Control: Kidney.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Calcitonin Receptor (CALCR)

    Andere Bezeichnung

    Calcitonin Receptor

    Hintergrund

    Calcitonin receptor is a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. The calcitonin receptor is expressed in kidney, central and peripheral nervous systems and on osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in foetal morphogenesis.Synonyms: CALCR, CT-R, CTR

    Gen-ID

    799

    NCBI Accession

    NP_001158209

    UniProt

    P30988

    Pathways

    cAMP Metabolic Process
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