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MCAM Antikörper (N-Term)

MCAM Reaktivität: Human FACS, IHC (fro), EIA Wirt: Maus Monoclonal OJ79c unconjugated

Produktnummer ABIN119671

Datenblatt (PDF)

Target Alle MCAM Antikörper anzeigen

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Bindungsspezifität
16

13

10

6

4

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-5, N-Term
Reaktivität
129

54

48

15

14

9

8

6

5

2
Human
Wirt
94

55

8

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
87

73
Monoklonal
Konjugat
73

13

12

9

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MCAM Antikörper ist unkonjugiert
Applikation
92

74

68

45

23

17

16

11

7

5

4

4

3

2

2

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität

This antibody recognizes the 118 kDa cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumor progression.

Aufreinigung

Affinity chromatography on Protein G

Immunogen

Recombinant human MUC18 (D1-D5) Fc protein. Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.

Klon

OJ79c

Isotyp

IgG1

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Applikationshinweise

Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 106 cells. Immunohistochemistry on frozen sections. Recommended positive control tissue: Melanoma. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, None, None

Konservierungsmittel

Azide free

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store the antibody at -20 °C only.
Target

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung

CD146 (MCAM Produkte)

Synonyme

CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper

Hintergrund

CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen

Gen-ID

4162

NCBI Accession

NP_006491

UniProt

P43121