MCAM Antikörper (N-Term)
-
- Target Alle MCAM Antikörper anzeigen
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
-
Bindungsspezifität
- AA 1-5, N-Term
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MCAM Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes the 118 kDa cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumor progression.
- Aufreinigung
- Affinity chromatography on Protein G
- Immunogen
- Recombinant human MUC18 (D1-D5) Fc protein. Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.
- Klon
- OJ79c
- Isotyp
- IgG1
- Top Product
- Discover our top product MCAM Primärantikörper
-
-
- Applikationshinweise
-
Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 106 cells. Immunohistochemistry on frozen sections. Recommended positive control tissue: Melanoma. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, None, None
- Konservierungsmittel
- Azide free
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody at -20 °C only.
-
- Target
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Andere Bezeichnung
- CD146 (MCAM Produkte)
- Hintergrund
- CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
- Gen-ID
- 4162
- NCBI Accession
- NP_006491
- UniProt
- P43121
-