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CD147 Antikörper

BSG Reaktivität: Human WB, FACS, IF, IP, IHC (p) Wirt: Maus Monoclonal MEM-M6-1 unconjugated
Produktnummer ABIN119254
  • Target Alle CD147 (BSG) Antikörper anzeigen
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    Reaktivität
    • 155
    • 46
    • 42
    • 17
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 86
    • 84
    • 9
    Maus
    Klonalität
    • 105
    • 71
    • 3
    Monoklonal
    Konjugat
    • 93
    • 13
    • 11
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD147 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 92
    • 41
    • 38
    • 33
    • 25
    • 18
    • 14
    • 13
    • 12
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody recognises the CD147 cell surface antigen.
    Aufreinigung
    Affinity Chromatography on Protein G
    Immunogen
    CD147Rg, consisting of the cDNA coding for the hinge region, CH2 and CH3 domains of Human IgG1.
    Klon
    MEM-M6-1
    Isotyp
    IgG1
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  • Applikationshinweise
    Flow cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Western Blot: under non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Schneiderhan, Scheler, Holzmann, Marx, Gschwend, Bucholz, Gress, Seufferlein, Adler, Oswald: "CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models." in: Gut, Vol. 58, Issue 10, pp. 1391-8, (2009) (PubMed).

  • Target
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    Andere Bezeichnung
    CD147 (BSG Produkte)
    Hintergrund
    CD147 is a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor
    Gen-ID
    682
    NCBI Accession
    NP_001719
    UniProt
    P35613
    Pathways
    S100 Proteine
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