CD147 Antikörper

Produktnummer ABIN119254

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD147 in WB, FACS, IF, IP und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für CD147 Antikörper (ABIN119254)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: MEM-M6-1

Produktdetails anti-CD147 Antikörper

Spezifität: This antibody recognises the CD147 cell surface antigen.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: CD147Rg, consisting of the cDNA coding for the hinge region, CH2 and CH3 domains of Human IgG1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Western Blot: under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CD147 Antikörper (ABIN119254)

Schneiderhan, Scheler, Holzmann, Marx, Gschwend, Bucholz, Gress, Seufferlein, Adler, Oswald: "CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models." in: Gut, Vol. 58, Issue 10, pp. 1391-8, (2009) (PubMed).

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: CD147

Hintergrund: CD147 is a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

Gen-ID: 682

NCBI Accession: NP_001719

UniProt: P35613

Pathways: S100 Proteine