CD147 Antikörper

Produktnummer ABIN119252

Produktdetails anti-CD147 Antikörper

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody recognizes the Human CD147 cell surface antigen, a 50-60 kDa glycoprotein also known as neurothelin and basigin.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: CD147Rg, consisting of the cDNA coding for the hinge region, CH2 and CH3 domains of Human IgG1.

Klon: MEM-M6-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 106 cells. Immunoprecipitation. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 without preservatives, None

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Referenzen für anti-CD147 Antikörper (ABIN119252)

Schneiderhan, Scheler, Holzmann, Marx, Gschwend, Bucholz, Gress, Seufferlein, Adler, Oswald: "CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models." in: Gut, Vol. 58, Issue 10, pp. 1391-8, (2009) (PubMed).

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: CD147 (BSG Produkte)

Synonyme: EMMPRIN antikoerper, RPE7 antikoerper, 5F7 antikoerper, CD147 antikoerper, M6 antikoerper, OK antikoerper, TCSF antikoerper, AI115436 antikoerper, AI325119 antikoerper, HT-7 antikoerper, 5A11 antikoerper, CE9 antikoerper, HT7 antikoerper, Ox47R antikoerper, basignin antikoerper, wu:fb26a05 antikoerper, wu:fo98e12 antikoerper, bsg antikoerper, prso03 antikoerper, basigin (Ok blood group) antikoerper, basigin antikoerper, basigin (Ok blood group) S homeolog antikoerper, BSG antikoerper, Bsg antikoerper, bsg antikoerper, bsg.S antikoerper

Hintergrund: CD147 is a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

Gen-ID: 682

NCBI Accession: NP_001719

UniProt: P35613

Pathways: S100 Proteine